ELF2

Across TCGA pan-cancer cohorts, ELF2 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated ELF2 data layer compared with 4 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ELF2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ELF2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCEC show a favorable association.

KIRC, UCEC, and KIRP are the cancer types where ELF2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.724	0.553	<.001	81	view →
UCEC	OS	Median	III,IV	0.898	0.757	.001	56	view →
KIRP	DFS	Quartile	All	0.618	0.823	.006	38	view →
UVM	DFS	Quartile	III,IV	0.170	0.832	<.001	38	view →
LGG	OS	Quartile	All	0.440	0.679	<.001	35	view →
HNSC	DFS	Median	IV	0.720	0.557	.001	34	view →
SKCM	DFS	Quartile	All	0.272	0.159	.005	29	view →
BRCA	DFS	Quartile	III,IV	0.956	0.755	.004	25	view →
LAML	DFS	Median	All	0.666	0.452	.014	24	view →
LUAD	OS	Quartile	II,III,IV	0.720	0.479	.014	21	view →
LUSC	DFS	Tertile	III,IV	0.565	1.000	.009	15	view →
READ	OS	Median	IV	0.824	0.455	.005	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

ELF2–KIRC (OS)

Open the KIRC breakdown →