Across TCGA patient cohorts, ELANE RNA expression is significantly associated with the protein abundance of many other proteins, with 10,177 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ELANE-associated proteins across cancer lineages are TNXB, SORBS1, and SYNPO2. Each is linked with ELANE in more than 5 cancer types. Because this analysis shows association rather than direction, both ELANE-to-partner and partner-to-ELANE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ELANE→partner) and Y-score (partner→ELANE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TNXB →	+0.854	+0.589	<.001	.007	3	6
COAD	SORBS1 →	+0.696	+0.285	<.001	.001	3	5
HNSC	SYNPO2 →	+0.764	+0.227	<.001	.006	3	5
OV	CAVIN3 →	+0.692	+0.197	<.001	.001	3	5
OV	EHD2 →	+0.762	+0.217	<.001	<.001	3	5
LSCC	EHD2_S438 →	+0.730	+0.234	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,177 associations by consensus.

Exploration

ELANE survival (RNA) · tumor vs normal (RNA) · all ELANE data types