EIF5A2

Across TCGA patient cohorts, EIF5A2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,365 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF5A2-associated genes across cancer lineages are SEPTIN4, FN1, and NKD2. Each is linked with EIF5A2 in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF5A2-to-partner and partner-to-EIF5A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF5A2 versus SEPTIN4 in GBM, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5A2→partner) and Y-score (partner→EIF5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEPTIN4 →	+1.157	+0.653	<.001	.001	3	6
OV	FN1 →	+1.680	+0.695	<.001	<.001	3	6
UCEC	NKD2 →	+1.841	+1.104	<.001	<.001	3	6
UCEC	SPOCK1 →	+1.478	+0.892	.004	<.001	3	6
OV	RCN3 →	+1.278	+0.871	<.001	<.001	3	6
OV	COL6A3 →	+1.425	+0.654	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,365 associations by consensus.

EIF5A2 vs SEPTIN4 — GBM

Explore this scatter interactively →