EIF4E1B

Across TCGA patient cohorts, EIF4E1B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,345 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EIF4E1B-associated proteins across cancer lineages are SKP1, S100A1, and SENP1_S57. Each is linked with EIF4E1B in more than 2 cancer types. Because this analysis shows association rather than direction, both EIF4E1B-to-partner and partner-to-EIF4E1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4E1B versus SKP1 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4E1B→partner) and Y-score (partner→EIF4E1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SKP1 →	+0.214	+0.222	<.001	<.001	3	3
OV	S100A1 →	+1.022	+0.207	.001	<.001	3	2
GBM	SENP1_S57 →	-0.503	-0.216	.001	<.001	3	2
GBM	ITGB1 →	-0.332	-0.174	.004	.003	2	3
OV	ITPR3_S1843 →	-1.122	-0.242	.001	.005	3	2
OV	LTBP1 →	-0.496	-0.185	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,345 associations by consensus.

EIF4E1B vs SKP1 — GBM

Explore this scatter interactively →