EIF4E1B

Across TCGA patient cohorts, EIF4E1B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,041 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EIF4E1B-associated GO terms across cancer lineages are Oxidative phosphorylation, Iron-sulfur cluster assembly, and Cellular respiration. Each is linked with EIF4E1B in more than 11 cancer types. Because this analysis shows association rather than direction, both EIF4E1B-to-partner and partner-to-EIF4E1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oxidative phosphorylation grouped by EIF4E1B-low versus EIF4E1B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4E1B→partner) and Y-score (partner→EIF4E1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Oxidative phosphorylation →	+0.061	+0.051	<.001	<.001	3	12
STAD	Iron-sulfur cluster assembly →	+0.041	+0.057	<.001	<.001	3	11
STAD	Cellular respiration →	+0.059	+0.053	<.001	<.001	3	10
LGG	Neurotransmitter secretion →	+0.073	+0.962	<.001	<.001	3	9
STAD	Establishment of protein localization to membrane →	+0.052	+0.049	<.001	<.001	3	9
STAD	Organelle membrane fusion →	+0.048	+0.049	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,041 associations by consensus.

Oxidative phosphorylation by EIF4E1B expression — STAD

Explore this box plot interactively →