EIF4A2

Across TCGA patient cohorts, EIF4A2 protein abundance is significantly associated with the protein abundance of many other proteins, with 14,802 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EIF4A2-associated proteins across cancer lineages are AGO1, ARPC1A, and ADH5. Each is linked with EIF4A2 in more than 5 cancer types. Because this analysis shows association rather than direction, both EIF4A2-to-partner and partner-to-EIF4A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4A2 versus AGO1 in COAD, with a Pearson correlation of 0.34.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4A2→partner) and Y-score (partner→EIF4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	AGO1 →	+0.310	+0.310	<.001	<.001	3	6
PDAC	ARPC1A →	+0.492	+0.239	<.001	<.001	3	6
COAD	ADH5 →	+0.374	+0.294	<.001	<.001	3	5
HNSC	CUTA →	+0.565	+0.466	<.001	<.001	3	5
UCEC	DYNLT3 →	+0.421	+0.244	<.001	<.001	3	5
UCEC	ARG1 →	-0.777	-0.197	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,802 associations by consensus.

EIF4A2 vs AGO1 — COAD

Explore this scatter interactively →