EIF3KP1

Across TCGA patient cohorts, EIF3KP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,975 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible EIF3KP1-associated GO terms across cancer lineages are Negative regulation of Wnt signaling pathway, Negative regulation of cell growth, and Stem cell differentiation. Each is linked with EIF3KP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both EIF3KP1-to-partner and partner-to-EIF3KP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of Wnt signaling pathway grouped by EIF3KP1-low versus EIF3KP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3KP1→partner) and Y-score (partner→EIF3KP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of Wnt signaling pathway →	+0.043	+0.181	.001	<.001	2	18
TGCT	Negative regulation of cell growth →	+0.036	+0.312	<.001	<.001	3	17
ESCA	Stem cell differentiation →	+0.040	+0.158	.004	<.001	3	17
ESCA	Protein localization to cilium →	+0.026	+0.173	.001	<.001	3	17
STAD	Proton motive force-driven ATP synthesis →	+0.062	+0.173	.001	<.001	2	17
STAD	Peptidyl-proline modification →	+0.041	+0.177	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,975 associations by consensus.

Negative regulation of Wnt signaling pathway by EIF3KP1 expression — ESCA

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