EIF3KP1

Across TCGA pan-cancer cohorts, EIF3KP1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of EIF3KP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where EIF3KP1 RNA is repressed in tumor relative to normal tissue. In most cancer types EIF3KP1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, KIRC, and LUSC are the cancer types where EIF3KP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIF3KP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.504	<.001	11	view →
KIRC	All	All	+0.337	<.001	8	view →
LUSC	Female	II,III,IV	−0.825	<.001	7	view →
KICH	Female	All	−0.546	<.001	7	view →
THCA	Male	All	+0.284	.017	4	view →
HNSC	All	All	+0.104	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

EIF3KP1–LUAD

Open the LUAD breakdown →