EIF3KP1

Across TCGA pan-cancer cohorts, EIF3KP1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated EIF3KP1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher EIF3KP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EIF3KP1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

UVM, MESO, and KIRC are the cancer types where EIF3KP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.437	0.733	<.001	108	view →
MESO	OS	Quartile	II,III,IV	0.274	0.573	.001	63	view →
KIRC	DFS	Quartile	All	0.761	0.881	.001	61	view →
OV	OS	Tertile	II,III,IV	0.271	0.415	.002	56	view →
SKCM	OS	Median	III,IV	0.493	0.319	.002	30	view →
STAD	DFS	Tertile	All	0.599	0.787	.020	18	view →
HNSC	DFS	Tertile	All	0.506	0.766	.001	15	view →
CESC	OS	Tertile	II,III,IV	0.673	0.380	.018	12	view →
GBM	OS	Median	All	0.310	0.503	<.001	12	view →
ESCA	OS	Tertile	IV	0.738	0.264	.024	12	view →
CHOL	DFS	Median	III,IV	0.647	0.127	.006	12	view →
READ	DFS	Quartile	II,III,IV	0.693	0.896	.015	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

EIF3KP1–UVM (DFS)

Open the UVM breakdown →