EIF3I

Across TCGA patient cohorts, EIF3I protein abundance is significantly associated with the RNA expression of many other genes, with 14,511 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF3I-associated genes across cancer lineages are CXCR2, SYNPO2, and VNN2. Each is linked with EIF3I in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF3I-to-partner and partner-to-EIF3I results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3I versus CXCR2 in LSCC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3I→partner) and Y-score (partner→EIF3I) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CXCR2 →	-1.013	-0.156	<.001	<.001	3	7
COAD	SYNPO2 →	-1.168	-0.148	<.001	<.001	3	6
HNSC	VNN2 →	-0.946	-0.256	<.001	<.001	2	6
PDAC	CSF3R →	-1.184	-0.343	<.001	<.001	3	5
COAD	LYVE1 →	-1.194	-0.239	<.001	<.001	3	5
BRCA	MYCT1 →	-0.746	-0.145	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,511 associations by consensus.

EIF3I vs CXCR2 — LSCC

Explore this scatter interactively →