EIF3F

Across TCGA patient cohorts, EIF3F mutation is significantly associated with the RNA expression of many other genes, with 1,626 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible EIF3F-associated genes across cancer lineages are CDRT15P8, EEF1E1-BLOC1S5, and PLEKHH3. Each is linked with EIF3F in more than 2 cancer types. Because this analysis shows association rather than direction, both EIF3F-to-partner and partner-to-EIF3F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDRT15P8 grouped by EIF3F-low versus EIF3F-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3F→partner) and Y-score (partner→EIF3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CDRT15P8 →	+0.131	+5.357	<.001	.006	3	3
COAD	EEF1E1-BLOC1S5 →	+0.108	+5.516	<.001	.004	3	2
UCEC	PLEKHH3 →	+0.776	+3.332	<.001	.005	3	2
UCEC	ANKRD24 →	+0.665	+3.332	<.001	.005	3	2
UCEC	SNRPGP17 →	+0.334	+2.686	.001	.002	3	2
UCEC	RN7SL248P →	+0.119	+4.307	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,626 associations by consensus.

CDRT15P8 by EIF3F expression — COAD

Explore this box plot interactively →