EIF2S3

Across TCGA patient cohorts, EIF2S3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,609 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF2S3-associated proteins across cancer lineages are SYAP1, DDX3X, and HUWE1. Each is linked with EIF2S3 in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF2S3-to-partner and partner-to-EIF2S3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2S3 versus SYAP1 in BRCA, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2S3→partner) and Y-score (partner→EIF2S3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SYAP1 →	+0.437	+0.465	<.001	<.001	3	7
GBM	DDX3X →	+0.285	+0.406	<.001	<.001	3	6
OV	HUWE1 →	+0.247	+0.548	<.001	.003	3	6
LSCC	KDM5C_S301 →	+0.655	+0.542	<.001	<.001	3	6
GBM	RPS4Y1 →	-1.158	-0.306	<.001	<.001	3	5
BRCA	SMS →	+0.556	+0.448	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,609 associations by consensus.

EIF2S3 vs SYAP1 — BRCA

Explore this scatter interactively →