EIF2AK3

Across TCGA patient cohorts, EIF2AK3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,734 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EIF2AK3-associated genes across cancer lineages are ZCCHC24, DPYSL2, and IFFO1. Each is linked with EIF2AK3 in more than 3 cancer types. Because this analysis shows association rather than direction, both EIF2AK3-to-partner and partner-to-EIF2AK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2AK3 versus ZCCHC24 in LUAD, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2AK3→partner) and Y-score (partner→EIF2AK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZCCHC24 →	-0.589	-0.371	<.001	<.001	3	4
LSCC	DPYSL2 →	-0.557	-0.291	.001	<.001	3	4
LUAD	IFFO1 →	-0.526	-0.422	<.001	<.001	3	3
LUAD	NOD1 →	-0.476	-0.287	<.001	<.001	3	3
GBM	SEPTIN4 →	-0.936	-0.238	<.001	<.001	3	3
GBM	RASGRF2 →	-0.689	-0.279	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,734 associations by consensus.

EIF2AK3 vs ZCCHC24 — LUAD

Explore this scatter interactively →