EHBP1

Across TCGA patient cohorts, EHBP1 mutation is significantly associated with the RNA expression of many other genes, with 4,492 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EHBP1-associated genes across cancer lineages are ZWINT, PAMR1, and LRRN4CL. Each is linked with EHBP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EHBP1-to-partner and partner-to-EHBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZWINT grouped by EHBP1-low versus EHBP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHBP1→partner) and Y-score (partner→EHBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZWINT →	+0.737	+1.959	<.001	<.001	3	4
UCEC	PAMR1 →	-0.619	-1.253	.008	.006	3	4
UCEC	LRRN4CL →	-0.465	-1.733	.006	<.001	3	4
LUAD	PPIL2 →	+0.438	+3.541	.009	.002	3	3
LUAD	MIS18A →	+0.627	+3.482	.002	.002	3	3
STAD	TSPY26P →	-0.836	-3.284	.007	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,492 associations by consensus.

ZWINT by EHBP1 expression — UCEC

Explore this box plot interactively →