EHBP1

Across TCGA pan-cancer cohorts, EHBP1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated EHBP1 data layer compared with 6 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher EHBP1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated EHBP1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SARC show a favorable association.

KIRC, BLCA, and ACC are the cancer types where EHBP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.743	0.523	<.001	158	view →
BLCA	OS	Median	All	0.531	0.684	<.001	140	view →
ACC	DFS	Median	All	0.299	0.833	<.001	109	view →
LUAD	OS	Median	All	0.226	0.461	<.001	78	view →
CESC	DFS	Median	All	0.424	0.651	<.001	40	view →
MESO	DFS	Median	All	0.295	0.478	.003	34	view →
STAD	OS	Quartile	II,III,IV	0.464	0.830	.011	28	view →
LUSC	OS	Tertile	III,IV	0.436	0.771	.001	27	view →
SARC	OS	Tertile	All	0.867	0.611	.001	20	view →
UCEC	DFS	Tertile	All	0.525	0.687	.003	20	view →
THYM	DFS	Median	II,III,IV	0.952	0.740	<.001	19	view →
LGG	OS	Median	All	0.748	0.874	<.001	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

EHBP1–KIRC (OS)

Open the KIRC breakdown →