EHBP1

Across TCGA pan-cancer cohorts, EHBP1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of EHBP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where EHBP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EHBP1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KIRC, HNSC, and KICH are the cancer types where EHBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EHBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.745	<.001	11	view →
HNSC	Male	All	+0.722	<.001	10	view →
KICH	Female	All	−2.364	<.001	8	view →
LUSC	Male	II,III,IV	+1.218	<.001	7	view →
UCEC	All	All	−1.562	<.001	6	view →
BRCA	All	III,IV	−1.030	<.001	6	view →
LUAD	Male	II,III,IV	+0.476	.008	2	view →
KIRP	Male	All	−0.403	.007	2	view →
ESCA	All	II,III,IV	−0.205	.036	2	view →
BLCA	All	IV	−0.835	.029	1	view →
ESCA	All	All	+0.646	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

EHBP1–KIRC

Open the KIRC breakdown →