EHBP1

Across TCGA cell cohorts, EHBP1 mutation is significantly associated with the RNA expression of many other genes, with 497 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EHBP1-associated genes across cancer lineages are ATP5F1E, PPAT, and NEIL2. Each is linked with EHBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EHBP1-to-partner and partner-to-EHBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP5F1E grouped by EHBP1-low versus EHBP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHBP1→partner) and Y-score (partner→EHBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ATP5F1E →	-0.696	-3.321	<.001	.003	3	2
LARGE_INTESTINE	PPAT →	+0.577	+2.129	.003	.007	3	2
LARGE_INTESTINE	NEIL2 →	+0.635	+2.743	.005	.001	3	2
LARGE_INTESTINE	EXO1 →	+0.714	+3.169	<.001	.006	3	2
LARGE_INTESTINE	SBK1 →	+0.839	+2.743	.002	.001	3	2
BLOOD_Leukemia	GZMK →	+0.407	+2.774	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 497 associations by consensus.

ATP5F1E by EHBP1 expression — LARGE_INTESTINE

Explore this box plot interactively →