EGFLAM

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EGFLAM protein abundance is significantly associated with the RNA expression of many other genes, with 8,055 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EGFLAM-associated genes across cancer lineages are FLT1, CD93, and ANGPTL2. Each is linked with EGFLAM in more than 4 cancer types. Because this analysis shows association rather than direction, both EGFLAM-to-partner and partner-to-EGFLAM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGFLAM versus FLT1 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFLAM→partner) and Y-score (partner→EGFLAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAFLT1 →+0.899+0.545<.001<.00135
BRCACD93 →+1.182+0.478<.001<.00135
OVANGPTL2 →+0.949+0.468.003.00635
BRCAAFAP1L1 →+0.773+0.452<.001<.00135
BRCABCL6B →+0.795+0.520<.001<.00135
BRCACD34 →+0.956+0.496<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,055 associations by consensus.

EGFLAM vs FLT1 — BRCA

Per-sample scatter of EGFLAM vs FLT1 in BRCA (Pearson r = 0.41).

Explore this scatter interactively →

Exploration