EGFLAM

Across TCGA pan-cancer cohorts, EGFLAM RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated EGFLAM data layer compared with 11 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher EGFLAM RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EGFLAM expression acts as an unfavorable survival marker, although some lineages such as HNSC and THCA show a favorable association.

STAD, UVM, and KIRP are the cancer types where EGFLAM RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	All	0.453	0.651	<.001	128	view →
UVM	DFS	Median	All	0.380	0.752	<.001	123	view →
KIRP	DFS	Median	All	0.762	1.000	<.001	93	view →
BLCA	OS	Median	All	0.540	0.674	.001	55	view →
HNSC	DFS	Median	II,III,IV	0.403	0.245	.008	50	view →
THCA	DFS	Median	All	0.929	0.656	.002	42	view →
UCEC	DFS	Median	IV	0.831	0.574	.029	24	view →
LGG	OS	Median	All	0.354	0.535	<.001	20	view →
LIHC	OS	Median	III,IV	0.660	0.402	.005	19	view →
COAD	DFS	Tertile	II,III,IV	0.691	0.814	.021	18	view →
UCS	DFS	Median	II,III,IV	0.537	0.150	.004	18	view →
CESC	DFS	Quartile	All	0.750	0.896	.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

EGFLAM–STAD (DFS)

Open the STAD breakdown →