EGFL7

Across TCGA patient cohorts, EGFL7 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible EGFL7-associated genes across cancer lineages are MIR365A, RNU6-1056P, and RNU6-1201P. Each is linked with EGFL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both EGFL7-to-partner and partner-to-EGFL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR365A grouped by EGFL7-low versus EGFL7-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFL7→partner) and Y-score (partner→EGFL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR365A →	+0.463	+4.915	<.001	.002	3	1
LIHC	RNU6-1056P →	+0.373	+4.648	<.001	.004	3	1
LIHC	RNU6-1201P →	+0.346	+4.776	.001	.003	3	1
LIHC	MIR581 →	+0.388	+5.066	<.001	.001	3	1
LIHC	PPP1R26P5 →	+0.012	+5.149	<.001	.003	3	1
LIHC	LINC01866 →	+0.226	+4.733	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

MIR365A by EGFL7 expression — LIHC

Explore this box plot interactively →