EFS

Across TCGA patient cohorts, EFS RNA expression is significantly associated with the protein abundance of many other proteins, with 19,698 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EFS-associated proteins across cancer lineages are EFS_S287, EFS_S298, and EFS_S331. Each is linked with EFS in more than 6 cancer types. Because this analysis shows association rather than direction, both EFS-to-partner and partner-to-EFS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFS versus EFS_S287 in CCRCC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EFS→partner) and Y-score (partner→EFS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	EFS_S287 →	+1.513	+1.735	<.001	.007	3	7
PDAC	EFS_S298 →	+0.928	+0.576	<.001	<.001	3	7
CCRCC	EFS_S331 →	+0.555	+1.056	<.001	<.001	3	6
OV	SARM1 →	+0.509	+1.173	<.001	<.001	3	6
UCEC	SORBS3 →	+0.575	+1.068	.001	<.001	3	5
OV	SRPX2 →	+0.713	+1.318	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,698 associations by consensus.

EFS vs EFS_S287 — CCRCC

Explore this scatter interactively →