EFS

Across TCGA patient cohorts, EFS protein abundance is significantly associated with the RNA expression of many other genes, with 7,595 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EFS-associated genes across cancer lineages are SLC22A17, SMIM10L2B, and TMEM41A. Each is linked with EFS in more than 4 cancer types. Because this analysis shows association rather than direction, both EFS-to-partner and partner-to-EFS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFS versus SLC22A17 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFS→partner) and Y-score (partner→EFS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC22A17 →	+1.121	+0.432	<.001	.001	3	5
BRCA	SMIM10L2B →	+0.488	+0.347	<.001	<.001	3	4
OV	TMEM41A →	+0.645	+0.816	<.001	.001	3	3
OV	TMEM92-AS1 →	+0.767	+0.882	.002	.004	3	3
LSCC	LINC00519 →	+1.342	+0.425	<.001	<.001	3	3
HNSC	UST →	+0.862	+0.489	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,595 associations by consensus.

EFS vs SLC22A17 — BRCA

Explore this scatter interactively →