EFR3A

Across TCGA patient cohorts, EFR3A protein abundance is significantly associated with the RNA expression of many other genes, with 10,164 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFR3A-associated genes across cancer lineages are MNS1, MEX3A, and KLHL14. Each is linked with EFR3A in more than 4 cancer types. Because this analysis shows association rather than direction, both EFR3A-to-partner and partner-to-EFR3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFR3A versus MNS1 in LSCC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFR3A→partner) and Y-score (partner→EFR3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MNS1 →	-0.695	-0.318	<.001	<.001	3	5
LSCC	MEX3A →	-1.215	-0.251	<.001	.001	3	5
UCEC	KLHL14 →	-0.703	-0.233	.006	.004	3	4
UCEC	SETDB1 →	-0.432	-0.275	<.001	<.001	3	4
GBM	RBBP4 →	-0.425	-0.270	<.001	<.001	3	4
UCEC	ZNF496 →	-0.556	-0.329	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,164 associations by consensus.

EFR3A vs MNS1 — LSCC

Explore this scatter interactively →