EFNA5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EFNA5 mutation is significantly associated with the RNA expression of many other genes, with 2,056 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFNA5-associated genes across cancer lineages are RNA5SP414, RNA5SP239, and RN7SL584P. Each is linked with EFNA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFNA5-to-partner and partner-to-EFNA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA5→partner) and Y-score (partner→EFNA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARNA5SP414 →+0.143+7.471.001.00832
COADRNA5SP239 →+0.623+7.741<.001.00932
COADRN7SL584P →+1.423+7.741<.001.00932
COADRN7SKP260 →+0.239+7.741<.001.00932
READMED28P4 →+0.398+5.039<.001.00832
BLCAHERC2P11 →+0.069+4.973<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,056 associations by consensus.

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