Across TCGA cell cohorts, EFCAB7 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EFCAB7-associated genes across cancer lineages are ADH1A, FAM205A, and OR2AK2. Each is linked with EFCAB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB7-to-partner and partner-to-EFCAB7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB7→partner) and Y-score (partner→EFCAB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ADH1A →	+0.132	+3.242	<.001	.003	3	1
LARGE_INTESTINE	FAM205A →	+0.023	+3.614	<.001	.006	3	1
OVARY	OR2AK2 →	+0.062	+4.029	<.001	.009	3	1
OVARY	OR2H1 →	+0.027	+4.029	<.001	.009	3	1
LUNG_NSCLC_LUAD	GABRA6 →	+0.064	+5.189	<.001	<.001	3	1
LUNG_NSCLC_LUAD	FEZF2 →	+0.016	+5.189	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

EFCAB7 survival (RNA) · tumor vs normal (RNA) · all EFCAB7 data types