EDC4

Across TCGA cell cohorts, EDC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,915 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EDC4-associated GO terms across cancer lineages are mRNA transport, Nuclear export, and Positive regulation of nuclear cell cycle DNA replication. Each is linked with EDC4 in more than 17 cancer types. Because this analysis shows association rather than direction, both EDC4-to-partner and partner-to-EDC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA transport grouped by EDC4-low versus EDC4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EDC4→partner) and Y-score (partner→EDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	mRNA transport →	+0.117	+1.079	<.001	<.001	3	18
BLOOD_Lymphoma	Nuclear export →	+0.079	+0.811	<.001	<.001	3	18
BONE	Positive regulation of nuclear cell cycle DNA replication →	+0.159	+1.066	<.001	<.001	3	18
BONE	mRNA alternative polyadenylation →	+0.085	+0.948	<.001	<.001	3	18
BONE	Telomere organization →	+0.114	+1.333	<.001	<.001	3	17
BONE	Subtelomeric heterochromatin formation →	+0.125	+0.932	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,915 associations by consensus.

mRNA transport by EDC4 expression — BONE

Explore this box plot interactively →