ECI2-DT

Across TCGA patient cohorts, ECI2-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 7,405 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ECI2-DT-associated proteins across cancer lineages are ECI2, TOP1_S394, and MAP1B_S1625. Each is linked with ECI2-DT in more than 5 cancer types. Because this analysis shows association rather than direction, both ECI2-DT-to-partner and partner-to-ECI2-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECI2-DT versus ECI2 in UCEC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ECI2-DT→partner) and Y-score (partner→ECI2-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ECI2 →	+0.999	+0.612	<.001	<.001	3	6
GBM	TOP1_S394 →	-0.485	-0.424	.005	.005	3	3
LSCC	MAP1B_S1625 →	+1.000	+0.204	<.001	.001	3	3
LSCC	MAP1B_S992 →	+0.871	+0.243	<.001	<.001	3	3
LSCC	MAP2 →	+0.769	+0.191	<.001	.004	3	3
LSCC	MAP2_S1155 →	+1.220	+0.206	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,405 associations by consensus.

ECI2-DT vs ECI2 — UCEC

Explore this scatter interactively →