ECHDC3

Across TCGA patient cohorts, ECHDC3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,606 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ECHDC3-associated genes across cancer lineages are SNCG, DPYS, and RGN. Each is linked with ECHDC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ECHDC3-to-partner and partner-to-ECHDC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ECHDC3 versus SNCG in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ECHDC3→partner) and Y-score (partner→ECHDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SNCG →	+2.109	+0.665	.001	<.001	3	4
CCRCC	DPYS →	+1.682	+0.476	<.001	<.001	3	4
CCRCC	RGN →	+1.109	+0.427	<.001	.003	3	4
CCRCC	AOX1 →	+1.519	+0.420	<.001	<.001	3	4
BRCA	FOLR1 →	+2.118	+0.773	<.001	<.001	3	3
OV	SMC4 →	-0.811	-0.581	.004	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,606 associations by consensus.

ECHDC3 vs SNCG — OV

Explore this scatter interactively →