EAPP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EAPP protein abundance is significantly associated with the protein abundance of many other proteins, with 19,282 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EAPP-associated proteins across cancer lineages are CCNT1, SNRPD2, and HIRIP3_S125. Each is linked with EAPP in more than 5 cancer types. Because this analysis shows association rather than direction, both EAPP-to-partner and partner-to-EAPP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EAPP versus CCNT1 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EAPP→partner) and Y-score (partner→EAPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACCNT1 →+0.468+0.378<.001<.00136
UCECSNRPD2 →+0.270+0.299<.001<.00136
UCECHIRIP3_S125 →+0.687+0.225<.001<.00136
BRCAUBR7 →+0.415+0.371<.001<.00136
LSCCPRPF6 →+0.274+0.340<.001<.00136
UCECACIN1 →+0.264+0.301<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,282 associations by consensus.

EAPP vs CCNT1 — BRCA

Per-sample scatter of EAPP vs CCNT1 in BRCA (Pearson r = 0.41).

Explore this scatter interactively →

Exploration