Across TCGA patient cohorts, DZIP3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,592 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DZIP3-associated genes across cancer lineages are DPP4, RIIAD1, and RGN. Each is linked with DZIP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both DZIP3-to-partner and partner-to-DZIP3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DZIP3→partner) and Y-score (partner→DZIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DPP4 →	+1.322	+0.965	<.001	<.001	3	3
UCEC	RIIAD1 →	+1.253	+0.325	.003	.002	3	3
PDAC	RGN →	+0.717	+0.492	.001	.002	3	3
OV	SSPN →	+0.632	+0.727	.006	.005	3	2
PDAC	SLC3A1 →	+0.398	+0.395	.003	.001	3	2
OV	TMX2P1 →	-0.404	-0.817	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,592 associations by consensus.

Exploration

DZIP3 survival (RNA) · tumor vs normal (RNA) · all DZIP3 data types