thioredoxin related transmembrane protein 2 pseudogene 1Genealiases: []
Q-omics provides the consensus-scored TMX2P1 profile across patient tissues and cancer cell-line models. TMX2P1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, TMX2P1 is differentially expressed in 9, with the highest sampling consensus in COAD. Additionally, TMX2P1 RNA expression shows 20,382 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and COAD as cancer lineages where TMX2P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TMX2P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TMX2P1 survival associations across molecular data types. TMX2P1 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TMX2P1 RNA expression–survival associations across cancer types. High TMX2P1 expression shows unfavorable associations in ACC, CESC and LIHC, but favorable associations in KIRC, LUAD and READ. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for TMX2P1 RNA expression.
This table summarizes TMX2P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for TMX2P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TMX2P1 shows lower tumor expression in KIRC and BRCA and higher tumor expression in COAD, CHOL, LIHC and HNSC. The COAD box plot shows higher TMX2P1 RNA expression in tumor versus normal tissue (log2 FC = +0.603, t-test p < 0.001).
This table shows molecular features associated with TMX2P1 in patient tissues and cancer cell lines. In patient samples, TMX2P1 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
