Across TCGA patient cohorts, DXO RNA expression is significantly associated with the protein abundance of many other proteins, with 12,262 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DXO-associated proteins across cancer lineages are CMTR1, GNL1, and DEK. Each is linked with DXO in more than 6 cancer types. Because this analysis shows association rather than direction, both DXO-to-partner and partner-to-DXO results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DXO→partner) and Y-score (partner→DXO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CMTR1 →	+0.460	+0.650	<.001	<.001	3	7
OV	GNL1 →	+0.343	+0.460	<.001	<.001	3	7
GBM	DEK →	+0.459	+0.395	<.001	<.001	3	6
PDAC	RNF5 →	+0.672	+0.414	<.001	<.001	3	6
OV	MDC1 →	+0.437	+0.611	<.001	<.001	3	6
GBM	DHX16 →	+0.268	+0.381	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,262 associations by consensus.

Exploration

DXO survival (RNA) · tumor vs normal (RNA) · all DXO data types