DUX4L50

Across TCGA patient cohorts, DUX4L50 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,620 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DUX4L50-associated proteins across cancer lineages are CELF2, DDOST, and SDE2. Each is linked with DUX4L50 in more than 3 cancer types. Because this analysis shows association rather than direction, both DUX4L50-to-partner and partner-to-DUX4L50 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUX4L50 versus CELF2 in CCRCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUX4L50→partner) and Y-score (partner→DUX4L50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CELF2 →	+0.233	+0.388	.001	.001	3	4
UCEC	DDOST →	-0.438	-0.648	<.001	.006	3	4
LSCC	SDE2 →	+0.211	+0.677	<.001	<.001	3	4
UCEC	ELF1 →	+0.225	+0.919	<.001	<.001	3	4
COAD	DOCK2 →	+0.332	+0.402	<.001	.004	3	4
GBM	AFAP1L1 →	-0.499	-1.008	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,620 associations by consensus.

DUX4L50 vs CELF2 — CCRCC

Explore this scatter interactively →