DUSP5

Across TCGA cell cohorts, DUSP5 mutation is significantly associated with the mutation status of many other genes, with 1,302 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DUSP5-associated genes across cancer lineages are HECA, FSD1, and HCN4. Each is linked with DUSP5 in more than 3 cancer types. Because this analysis shows association rather than direction, both DUSP5-to-partner and partner-to-DUSP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HECA grouped by DUSP5-low versus DUSP5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP5→partner) and Y-score (partner→DUSP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HECA →	+4.309	+4.560	.007	.007	1	4
OVARY	FSD1 →	+4.977	+4.415	.007	.007	1	3
BLOOD_Leukemia	HCN4 →	+3.479	+4.932	.002	.002	1	3
BLOOD_Leukemia	NFIC →	+4.309	+4.560	.007	.007	1	3
BLOOD_Leukemia	CNNM4 →	+3.894	+5.247	.001	.001	1	3
BLOOD_Leukemia	SCUBE1 →	+3.309	+4.794	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,302 associations by consensus.

HECA by DUSP5 expression — BLOOD_Leukemia

Explore this box plot interactively →