DUSP21

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DUSP21 mutation is significantly associated with the RNA expression of many other genes, with 3,287 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DUSP21-associated genes across cancer lineages are MIR6129, H2BC17, and UHRF1. Each is linked with DUSP21 in more than 1 cancer types. Because this analysis shows association rather than direction, both DUSP21-to-partner and partner-to-DUSP21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUSP21→partner) and Y-score (partner→DUSP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6129 →+0.290+1.633<.001.00332
UCECH2BC17 →+0.574+2.389.006<.00132
UCECUHRF1 →+1.083+2.389<.001<.00132
COADRPS29P31 →+0.446+5.357<.001.00632
CESCMTND4P29 →+0.060+5.103<.001.00832
UCECPOC1A →+0.478+2.264.004.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,287 associations by consensus.

Exploration