DUS4L

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DUS4L protein abundance is significantly associated with the RNA expression of many other genes, with 1,884 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DUS4L-associated genes across cancer lineages are ZC3H12B, CAB39L, and LMF1. Each is linked with DUS4L in more than 1 cancer types. Because this analysis shows association rather than direction, both DUS4L-to-partner and partner-to-DUS4L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUS4L versus ZC3H12B in LUAD, with a Pearson correlation of -0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUS4L→partner) and Y-score (partner→DUS4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADZC3H12B →-0.437-0.368<.001<.00131
LUADCAB39L →-0.960-0.447.007.00431
LUADLMF1 →-1.075-0.444.001.00131
LUADHOMER2 →-1.641-0.326<.001.00231
LUADZNF106 →-0.492-0.317<.001.00331
LUADFCGRT →-1.221-0.581<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,884 associations by consensus.

DUS4L vs ZC3H12B — LUAD

Per-sample scatter of DUS4L vs ZC3H12B in LUAD (Pearson r = -0.79).

Explore this scatter interactively →

Exploration