DUOXA2

Across TCGA patient cohorts, DUOXA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,404 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DUOXA2-associated proteins across cancer lineages are DUOX1, DUOX1_S634, and DUOX2. Each is linked with DUOXA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DUOXA2-to-partner and partner-to-DUOXA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUOXA2 versus DUOX1 in UCEC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUOXA2→partner) and Y-score (partner→DUOXA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DUOX1 →	+1.686	+1.198	<.001	.001	3	4
UCEC	DUOX1_S634 →	+1.409	+1.203	<.001	<.001	3	4
LUAD	DUOX2 →	+3.942	+4.207	<.001	<.001	3	4
LSCC	DUOXA2_S296 →	+1.926	+1.086	<.001	<.001	3	4
UCEC	UBE2O →	-0.197	-0.787	.006	.003	3	3
LSCC	NECTIN4 →	+0.732	+0.775	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,404 associations by consensus.

DUOXA2 vs DUOX1 — UCEC

Explore this scatter interactively →