DUOXA1

Across TCGA patient cohorts, DUOXA1 RNA expression is significantly associated with the RNA expression of many other genes, with 15,088 significant associations in total. THYM shows the largest number of these associations.

The most reproducible DUOXA1-associated genes across cancer lineages are DUOX1, DUOX2, and DUOXA2. Each is linked with DUOXA1 in more than 33 cancer types. Because this analysis shows association rather than direction, both DUOXA1-to-partner and partner-to-DUOXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUOXA1 versus DUOX1 in ESCA, with a Pearson correlation of 0.91.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DUOXA1→partner) and Y-score (partner→DUOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	DUOX1 →	+2.433	+2.775	<.001	<.001	3	34
STAD	DUOX2 →	+2.701	+1.236	<.001	<.001	3	31
STAD	DUOXA2 →	+2.447	+1.236	<.001	<.001	3	28
THYM	TNKS1BP1 →	+1.021	+1.438	<.001	<.001	3	21
MESO	CSPG4P10 →	+0.869	+1.750	<.001	<.001	3	20
ESCA	NECTIN4 →	+1.850	+2.290	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,088 associations by consensus.

DUOXA1 vs DUOX1 — ESCA

Explore this scatter interactively →