DUOXA1

Across TCGA patient cohorts, DUOXA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,359 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DUOXA1-associated proteins across cancer lineages are DUOX1, DUOX1_S634, and FAM89A. Each is linked with DUOXA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DUOXA1-to-partner and partner-to-DUOXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DUOXA1 versus DUOX1 in UCEC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DUOXA1→partner) and Y-score (partner→DUOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DUOX1 →	+0.947	+1.382	<.001	<.001	3	4
UCEC	DUOX1_S634 →	+1.463	+1.995	<.001	<.001	3	4
BRCA	FAM89A →	+0.668	+0.855	<.001	<.001	3	4
LSCC	NECTIN4 →	+0.582	+0.766	<.001	<.001	3	4
UCEC	PKP1_S185 →	+2.973	+1.220	<.001	<.001	3	4
LSCC	SPRR1A →	+1.393	+0.809	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,359 associations by consensus.

DUOXA1 vs DUOX1 — UCEC

Explore this scatter interactively →