DTX2P1-UPK3BP1-PMS2P11

Across TCGA patient cohorts, DTX2P1-UPK3BP1-PMS2P11 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DTX2P1-UPK3BP1-PMS2P11-associated genes across cancer lineages are PDCL2P1, RNU6-747P, and MIR4796. Each is linked with DTX2P1-UPK3BP1-PMS2P11 in more than 1 cancer types. Because this analysis shows association rather than direction, both DTX2P1-UPK3BP1-PMS2P11-to-partner and partner-to-DTX2P1-UPK3BP1-PMS2P11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCL2P1 grouped by DTX2P1-UPK3BP1-PMS2P11-low versus DTX2P1-UPK3BP1-PMS2P11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX2P1-UPK3BP1-PMS2P11→partner) and Y-score (partner→DTX2P1-UPK3BP1-PMS2P11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCL2P1 →	+0.183	+3.484	.001	.004	3	2
STAD	RNU6-747P →	+0.678	+5.463	<.001	.005	3	1
UCEC	MIR4796 →	+0.354	+3.771	<.001	.002	3	1
UCEC	LINC01899 →	+0.175	+2.812	<.001	.008	3	1
UCEC	SNORA59B →	+0.293	+3.861	<.001	.001	3	1
UCEC	URGCP-MRPS24 →	+0.304	+3.643	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

PDCL2P1 by DTX2P1-UPK3BP1-PMS2P11 expression — UCEC

Explore this box plot interactively →