DTX2P1-UPK3BP1-PMS2P11

Across TCGA pan-cancer cohorts, DTX2P1-UPK3BP1-PMS2P11 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of DTX2P1-UPK3BP1-PMS2P11’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where DTX2P1-UPK3BP1-PMS2P11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DTX2P1-UPK3BP1-PMS2P11 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRC, LIHC, and LUSC are the cancer types where DTX2P1-UPK3BP1-PMS2P11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DTX2P1-UPK3BP1-PMS2P11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.375	<.001	11	view →
LIHC	All	II,III,IV	+0.267	<.001	7	view →
LUSC	Male	All	+0.714	<.001	6	view →
STAD	All	All	+0.467	.006	6	view →
KIRP	All	All	+0.298	<.001	6	view →
CHOL	All	All	+0.742	<.001	5	view →
THCA	Female	II,III,IV	−0.397	<.001	4	view →
COAD	All	All	+0.330	<.001	4	view →
LUAD	All	All	+0.319	.002	4	view →
READ	All	All	+0.837	<.001	2	view →
PAAD	Male	All	+0.550	.037	2	view →
HNSC	Male	All	+0.298	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

DTX2P1-UPK3BP1-PMS2P11–KIRC

Open the KIRC breakdown →