DTX2

Across TCGA patient cohorts, DTX2 RNA expression is significantly associated with the RNA expression of many other genes, with 18,138 significant associations in total. ACC shows the largest number of these associations.

The most reproducible DTX2-associated genes across cancer lineages are ZDHHC12, GNB2, and RHOG. Each is linked with DTX2 in more than 29 cancer types. Because this analysis shows association rather than direction, both DTX2-to-partner and partner-to-DTX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTX2 versus ZDHHC12 in LGG, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX2→partner) and Y-score (partner→DTX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	ZDHHC12 →	+1.024	+0.640	<.001	<.001	3	30
ACC	GNB2 →	+0.899	+0.686	<.001	<.001	3	30
KICH	RHOG →	+0.722	+0.639	<.001	<.001	3	30
ESCA	DTX2P1 →	+0.909	+0.773	<.001	<.001	3	30
ACC	TEDC1 →	+1.057	+0.899	<.001	<.001	3	30
ACC	RANGAP1 →	+1.436	+0.722	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,138 associations by consensus.

DTX2 vs ZDHHC12 — LGG

Explore this scatter interactively →