DTX2

Across TCGA patient cohorts, DTX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,906 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DTX2-associated proteins across cancer lineages are NCF4, BAIAP2L1, and ANXA1_Y39. Each is linked with DTX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both DTX2-to-partner and partner-to-DTX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DTX2 versus NCF4 in CCRCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DTX2→partner) and Y-score (partner→DTX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NCF4 →	+0.511	+0.466	<.001	<.001	3	4
UCEC	BAIAP2L1 →	+0.625	+0.632	<.001	<.001	3	4
UCEC	ANXA1_Y39 →	+0.974	+0.582	<.001	<.001	3	4
CCRCC	PPP2R5A_S41 →	-0.739	-0.603	.001	.002	3	3
UCEC	PTK2_S840 →	-0.458	-0.481	.002	.002	3	3
PDAC	SSH1_S897 →	+0.968	+0.318	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,906 associations by consensus.

DTX2 vs NCF4 — CCRCC

Explore this scatter interactively →