DTWD1

Across TCGA patient cohorts, DTWD1 mutation is significantly associated with the RNA expression of many other genes, with 1,590 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DTWD1-associated genes across cancer lineages are RNA5SP410, RNA5SP417, and RN7SKP129. Each is linked with DTWD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DTWD1-to-partner and partner-to-DTWD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP410 grouped by DTWD1-low versus DTWD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DTWD1→partner) and Y-score (partner→DTWD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP410 →	+0.491	+2.136	.003	.003	3	2
UCEC	RNA5SP417 →	+0.619	+2.699	<.001	<.001	3	2
SKCM	RN7SKP129 →	+0.167	+4.680	<.001	.007	3	2
SKCM	LINC02629 →	+0.105	+4.730	<.001	.003	3	2
SKCM	FAM207CP →	+0.073	+4.970	<.001	.005	3	2
SKCM	SCP2D1 →	+0.063	+6.485	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,590 associations by consensus.

RNA5SP410 by DTWD1 expression — UCEC

Explore this box plot interactively →