DSN1

Across TCGA patient cohorts, DSN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,714 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DSN1-associated proteins across cancer lineages are PRIM2, CSE1L, and POLD1. Each is linked with DSN1 in more than 9 cancer types. Because this analysis shows association rather than direction, both DSN1-to-partner and partner-to-DSN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSN1 versus PRIM2 in GBM, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSN1→partner) and Y-score (partner→DSN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRIM2 →	+0.520	+0.579	<.001	<.001	3	10
LSCC	CSE1L →	+0.407	+0.651	<.001	<.001	3	10
BRCA	POLD1 →	+0.357	+0.420	<.001	<.001	3	10
GBM	MCM3 →	+0.814	+0.702	<.001	<.001	3	10
LUAD	MCM4 →	+0.827	+0.864	<.001	<.001	3	10
GBM	MCM6 →	+0.930	+0.741	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,714 associations by consensus.

DSN1 vs PRIM2 — GBM

Explore this scatter interactively →