DSG2-AS1

Across TCGA patient cohorts, DSG2-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,280 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DSG2-AS1-associated proteins across cancer lineages are DSG2, DSC2, and JUP. Each is linked with DSG2-AS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DSG2-AS1-to-partner and partner-to-DSG2-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DSG2-AS1 versus DSG2 in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DSG2-AS1→partner) and Y-score (partner→DSG2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DSG2 →	+0.669	+0.787	<.001	<.001	3	8
BRCA	DSC2 →	+1.030	+0.377	<.001	<.001	3	5
LSCC	JUP →	+0.879	+0.648	<.001	<.001	3	5
LUAD	FOXK1 →	+0.250	+0.258	<.001	.002	3	5
BRCA	CMSS1 →	+0.514	+0.334	<.001	<.001	3	5
HNSC	NUP160 →	+0.147	+0.651	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,280 associations by consensus.

DSG2-AS1 vs DSG2 — LSCC

Explore this scatter interactively →