DRC7

Across TCGA cell cohorts, DRC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,301 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DRC7-associated GO terms across cancer lineages are Regulation of TORC1 signaling, Regulation of organelle assembly, and Protein localization to cilium. Each is linked with DRC7 in more than 8 cancer types. Because this analysis shows association rather than direction, both DRC7-to-partner and partner-to-DRC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of TORC1 signaling grouped by DRC7-low versus DRC7-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DRC7→partner) and Y-score (partner→DRC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of TORC1 signaling →	+0.049	+0.243	.008	.001	2	9
CNS	Regulation of organelle assembly →	+0.023	+0.214	.001	.003	3	8
LUNG_NSCLC_LUAD	Protein localization to cilium →	+0.060	+0.309	<.001	<.001	3	7
KIDNEY	Regulation of TOR signaling →	+0.029	+0.651	.003	.004	3	7
CNS	Negative regulation of myoblast fusion →	+0.078	+0.211	<.001	.001	3	7
CNS	Regulation of myoblast fusion →	+0.082	+0.240	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,301 associations by consensus.

Regulation of TORC1 signaling by DRC7 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →