DPYD-IT1

Across TCGA patient cohorts, DPYD-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,425 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DPYD-IT1-associated proteins across cancer lineages are DPYD, DPYD_S905, and PPP1R18. Each is linked with DPYD-IT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both DPYD-IT1-to-partner and partner-to-DPYD-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPYD-IT1 versus DPYD in GBM, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYD-IT1→partner) and Y-score (partner→DPYD-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DPYD →	+1.079	+1.187	<.001	<.001	3	7
LSCC	DPYD_S905 →	+0.803	+0.865	<.001	<.001	3	7
UCEC	PPP1R18 →	+0.423	+0.844	<.001	.001	3	6
GBM	ARHGEF1 →	+0.272	+0.925	<.001	<.001	3	5
UCEC	SH3BGRL3 →	+0.364	+1.059	<.001	<.001	3	5
LSCC	CAPZB →	+0.210	+0.674	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,425 associations by consensus.

DPYD-IT1 vs DPYD — GBM

Explore this scatter interactively →