DPYD-AS2

Across TCGA patient cohorts, DPYD-AS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,563 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DPYD-AS2-associated proteins across cancer lineages are DPYD, PPP1R18, and DOK2. Each is linked with DPYD-AS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both DPYD-AS2-to-partner and partner-to-DPYD-AS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPYD-AS2 versus DPYD in GBM, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYD-AS2→partner) and Y-score (partner→DPYD-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DPYD →	+1.030	+1.220	<.001	<.001	3	7
UCEC	PPP1R18 →	+0.605	+1.122	<.001	<.001	3	6
UCEC	DOK2 →	+0.565	+0.769	<.001	<.001	3	6
HNSC	DPYD_S905 →	+1.198	+1.322	<.001	<.001	3	6
HNSC	FMNL1 →	+0.531	+0.810	<.001	<.001	3	6
UCEC	GBP2 →	+0.596	+0.762	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,563 associations by consensus.

DPYD-AS2 vs DPYD — GBM

Explore this scatter interactively →