DPYD-AS2

Across TCGA pan-cancer cohorts, DPYD-AS2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of DPYD-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where DPYD-AS2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DPYD-AS2 is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.

STAD and UCEC are the cancer types where DPYD-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DPYD-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.062	.029	2	view →
UCEC	All	All	−0.021	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

DPYD-AS2–STAD

Open the STAD breakdown →